Problems in Meiosis Lead to Disease

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This lesson is a variation on the traditional pipe-cleaner simulation ofmitosis/meiosis. Initially, students review the normal process of meiosis. Thestudents are then presented with monosomy and trisomy gametes and asked towork backwards through the stages of meiosis in order to determine where theerror may have occurred. Students are then introduced to the concept ofnondisjunction.